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gene exp pde4b rn00566785 m1  (Thermo Fisher)
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Thermo Fisher gene exp pde4b rn00566785 m1
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Gene Exp Pde4b Rn00566785 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pde4b kd rs09 group  (MedChemExpress)
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MedChemExpress pde4b kd rs09 group
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
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rnascope probe mm-pde4b-c1  (Advanced Cell Diagnostics Inc)
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Advanced Cell Diagnostics Inc rnascope probe mm-pde4b-c1
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
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rabbit anti rat pde4b  (Biorbyt)
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In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Rabbit Anti Rat Pde4b, supplied by Biorbyt, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pde4b  (Biorbyt)
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Biorbyt pde4b
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Pde4b, supplied by Biorbyt, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sirna targeting pde4b  (Shanghai GenePharma)
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Shanghai GenePharma sirna targeting pde4b
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Sirna Targeting Pde4b, supplied by Shanghai GenePharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pde4b-targeted pet probe [ 18 f]pf-06445974  (Pfizer Inc)
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Pfizer Inc pde4b-targeted pet probe [ 18 f]pf-06445974
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Pde4b Targeted Pet Probe [ 18 F]Pf 06445974, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pde4b/c/d antibody  (MyBiosource Biotechnology)
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MyBiosource Biotechnology pde4b/c/d antibody
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Pde4b/C/D Antibody, supplied by MyBiosource Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pde4b antibody  (GeneTex)
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GeneTex pde4b antibody
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
Pde4b Antibody, supplied by GeneTex, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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selective pde4b inhibitor a33  (Tocris)
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Tocris selective pde4b inhibitor a33
In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( <t>Pde4b</t> ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).
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In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( Pde4b ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).

Journal: Experimental neurology

Article Title: Daily acute intermittent hypoxia elicits age & sex-dependent changes in molecules regulating phrenic motor plasticity

doi: 10.1016/j.expneurol.2025.115240

Figure Lengend Snippet: In young males, dAIH exposure significantly reduced Q pathway associated 5HT2A receptor expression (Panel A). In young females, dAIH significantly reduced S to Q cross talk molecules – p38Map kinase β ( Mapk11 ) and phosphodiesterase ( Pde4b ) expression. Reduced phosphodiesterase expression could indirectly increase PKA or EPAC activity which could in turn increase S to Q inhibition (Panel B). In middle aged males, no significant effect of dAIH exposure was observed (Panel C). In contrast widespread gene expression changes with dAIH exposure were observed in middle aged females. dAIH reduced expression of 5HT2B and A2A receptor, Q to S cross talk molecules–PKCδ ( Prkcd ) and NADPH-p47 ( Ncf1 ), S to Q cross-talk molecules phosphodiesterase 4b, and fractalkine ( Cx3cl1 ) (Panel D).

Article Snippet: phosphodiesterase 4B , pde4b , S to Q crosstalk , Rn00566785_m1 , 70.

Techniques: Expressing, Activity Assay, Inhibition, Gene Expression